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趙 晉 教授
作者:趙晉    編輯:潘彩云     校審: 馮若飛 柏家林 哈玉梅 審簽: 馮若飛 柏家林 哈玉梅     發布時間:2024-01-31    訪問量:

個人基本情況:

趙晉,女,教授,博士,博士研究生導師,中國民族醫藥協會常務理事,中國環境誘變劑學會活性氧生物學效應專業委員會常委,國家民委領軍人才和甘肅省青年教師成才獎獲得者。主要從事DNA損傷和病原微生物致病機制方面的研究工作。主持國家自然科學基金4項,主持省部級科研項目4項。主編和參與編寫著作4部。先后在各級刊物上公開發表論文70余篇,其中SCI收錄論文20余篇。

教育經歷:

1986.9-1991.7在西北民族學院醫療系學習;

1997.9-2000.7 在蘭州醫學院微生物與免疫學專業攻讀碩士學位;

2000.9-2004.7 在蘭州大學細胞生物學專業攻讀博士學位;

2007.1-2008.1 赴加拿大哥倫比亞省癌癥研究中心從事博士后研究。

工作經歷:1991年至今在西北民族大學醫學部工作。

科研獎勵:獲得甘肅省科技進步三等獎2次、甘肅省高校科技進步一等獎和三等獎各1次、甘肅省醫學會科技進步三等獎1次、蘭州市科學技術進步三等獎1次、中國民族醫藥協會科學技術進步二等獎1次。

研究生培養情況:培養在讀博士2人,已培養碩士研究生17人。

主要學術成果:

1JinZhao, Zhong Guo, Hong Zhang, Zhenhua Wang, LeiSong, Jianxiu Ma, Shuyan Pei, Chenjing Wang. The potential value of the neutralcomet assay and γH2AX foci assay in assessing the radiosensitivity of carbonbeam in human tumor cell lines. RADIOL ONCOL. 2013 ,47(3):247-57.

2Zhong Guo, Jin Zhao(通訊作者) , Lei Song, Jian-Xiu Ma, Chen-Jing Wang,Shu-Yan Pei, Chao Jiang and Shang-Biao Li. Induction of H2AX phosphorylation intumor cells by gossypol acetic acid is mediated by phosphatidylinositol3-kinase (PI3K) family. Cancer Cell International. 2014 ,14:141.doi:10.1186/s12935-014-0141-5.

3ZHONG GUO, SHUYAN PEI, TIANBIN SI, JING LI,CHAO JIANG, SHANGBIAO LI and JIN ZHAO*(通訊作者).Expression of the γ-phosphorylated histone H2AX in gastric carcinoma andgastric precancerous lesions. Oncology Letters .9:1790-1794,2015. DOI: 10.3892/ol.2015.2896

4J.Zhao*,(通訊作者) Q. Wang, J. Li, T.B. Si, S.Y. Pei, Z. Guo,C. Jiang. Comparative study of phosphorylated histone H2AX expressions in thecervical cancer patients of pre- and postneoadjuvant chemotherapy. Eur. J.Gynaecol. Oncol . 2015;36(3):318-22. DOI: 10.12892/ejgo2689.2015

5JinZhao*, Zhong Guo, Qiang Wang, Tianbin Si, ShuyanPei, Chenjing Wang, Hongmei Qu, Jianbin Zhong, Ying Ma, Cong Nie, Dan Zhang.Human papillomavirus genotypes associated with cervical precancerous lesionsand cancer in the highest area of cervical cancer mortality, Longnan, China.Infectious Agents and Cancer 2017;12:8.

6JinZhao*, Zhong Guo, Shuyan Pei, Lei Song, ChenjingWang, Jianxiu Ma, Long Jin, Yanqing Ma, Renke He, Jianbin Zhong, Ying Ma, HongZhang. pATM and γH2AX are effective radiation biomarkers in assessing theradiosensitivity of 12C6+ in human tumor cells. Cancer Cell International. 2017,17:49.

7Fei Zhao· Jin Zhao· Lei Song· YaQing Zhang· Zhong Guo· KeHu Yang. The induction of apoptosis and autophagy in human hepatoma SMMC-7721 cells by combined treatment with vitamin C and polysaccharides extracted from Grifola frondosa. Apoptosis (2017) 22(11):1461–1472. (SCI)

8JinYing Liu#, Xiaokang Liu, Wei Ma, WeiKou, CaiLi Li, Jin Zhao*(通訊作者).Anticancer activity of cucurbitacin-A in ovarian cancer cell line SKOV3involves cell cycle arrest, apoptosis and inhibition of mTOR/PI3K/Akt signalingpathway. JBUON 2018; 23(1): 124-128.

9Zhao J, Guo Z, Wang Q, Si T, Pei S, Qu H, ShangL, Yang Y, Wang L. HPV infection associated DNA damage correlated with cervicalprecancerous lesions and cancer in the highest area of cervical cancermortality, Longnan, China. Cancer Management and Research. 2019, 11:7197-7210.

10尚立娜; 安利鋒; 張城; 龔川友;周彰映;田世馨;李曉琴;趙晉*(通訊作者).HPV16E7 的表達對宮頸癌變過程中CD163+巨噬細胞的浸潤及上皮間質轉化的影響, 中國組織化學與細胞化學雜志, 2019, 28(05): 1-8.

11尚立娜; 周彰映; 張城; 龔川友;田世馨;安利鋒;李曉琴;趙晉*(通訊作者). Bcl2轉錄抑制因子1、E-鈣黏蛋白在宮頸鱗狀細胞癌不同區域的表達及兩者與P16INK4a表達的關系, 第二軍醫大學學報, 2019,40(12): 1317-1324.

12JinYing Liu#, , Wei Ma, Wei Kou, LinaShang, Rui Huang, Jin Zhao*(通訊作者).Poly-amino acids coated gold nanorod and doxorubicin for synergisticphotodynamic therapy and chemotherapy in ovarian cancer cells. BioscienceReports (2019) 39 BSR20192521.

13Yaqing Zhang, Hongyun Gan, Fei Zhao,Xiaomei Ma, Xiaofeng Xie, Rui Huang, JinZhao*(通訊作者).CPEB4-Promoted Paclitaxel Resistance in Ovarian CancerIn Vitro Relies on Translational Regulation of CSAG2. Front Pharmacol. 2021 Jan13;11:600994.

14宋雷,郭忠,趙玉,李焱,付玉婷,趙晉*(通訊作者).BICC1基因與胃癌進展和預后相關性的生物信息學分析, 基因組學與應用生物學, 2021,40(12): 1317-1324.

15Fei Zhao, Zhong Guo, Zhong-Ren Ma, Ling-LiMa, Jin Zhao*(通訊作者).Antitumor activities of Grifola frondosa (Maitake) polysaccharide: Ameta-analysis based on preclinical evidence and quality assessment. Journal ofEthnopharmacology. 2021, 280:114395.

16Fei Zhao, Zhong Guo, Yaqing Zhang, Lei Song, Lingli Ma, Jin Zhao*. Anti-tumor and immunomodulatory effects of Grifola frondosa polysaccharide combined with vitamin C on Heps-bearing mice: Based on inducing apoptosis and autophagy. Journal of Functional Foods. 87 (2021) 104797. (SCI) (通訊作者)

17郭忠,馬建秀,馬艷慶,宋雷,汪晨凈,郭淼,夏溪,趙晉*(通訊作者).蘭州百合多糖片段對X射線誘導的小鼠骨髓有核細胞損傷的保護作用.[J]. 輻射研究與輻射工藝學報,2022,40(1):010302 (7).  (CSCD核心)

18Zilong Zhang, Linghong Zhu, Yanqing Ma, Bo Wang, Caihong Ci, Jingni Zhang, Yunsong Zhou, Chunjiang Dou, Qiaoling Gu, Yan An, Yongmei Lan, Jin Zhao*. Study on the Characteristics of Intestinal Flora Composition in Gastric Cancer Patients and Healthy People in the Qinghai Tibet Plateau. Applied Biochemistry and Biotechnology. 2022 Apr;194(4):1510-1526. (SCI) (通訊作者)

19Guo Z. Zhu T. Zhou Y. Si T. Wang Q. Qu H. Wang C. Zhao J*.Relationship between Human Papillomavirus Prevalence and DNA Damage in Cervical Cancer Population in Gansu Province, China. Intervirology. 2022;65:215-223.   (SCI) (通訊作者)

20王小恒,李裕,張芳,趙晉*(通訊作者),董開忠.氣候變暖與干旱復合脅迫對小麥幼苗亞細胞銅、錳動態積累和分布的影響.[J]. 應用與環境生物學報,2022, 28 (5): 1239 -1246.

21S Kang#, Z Guo#, F Zhao, L Song, L Lu, C Wang, Z Liu,?and J Zhao?. Lanzhou Lily Polysaccharide Fragment Protects Human Umbilical Vein Endothelial Cells from Radiation-Induced DNA Double Stranded Breaks.Human and Experimental Toxicology. Human & Experimental Toxicology. 2022;41: 1–10. (SCI) (通訊作者)

22Yanqing  Ma,  Caihong  Ci,  Yunsong  Zhou,  Zilong  Zhang, Qiaoling  Gu,  Xiao  Yang,  Fulong  An,  Yan  An,Yongmei  Lan*  and  Jin  Zhao 1,4*.Analysis of gut microbiotal diversity in healthy young adults in Sunan County, Gansu Province, China. Front. Cell. Infect. Microbiol., 2023;13:1-13. (SCI) (通訊作者)

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